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Merck KGaA diazepam-d 5
Diazepam D 5, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings—A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish Larvae
Article Snippet: NADP + was obtained from Biomol (Hamburg, Germany), trimipramine- d 3 was from LGC (Wesel, Germany), and dithiothreitol, reduced glutathione, superoxide dismutase, magnesium chloride (MgCl 2 ), dipotassium hydrogen phosphate (K 2 HPO 4 ), potassium dihydrogen phosphate (KH 2 PO 4 ), Tris hydrochloride, isocitrate dehydrogenase, isocitrate, 3′-phosphoadenosine-5′-phosphosulfate (PAPS), S -(5′-adenosyl)-L-methionine (SAM), dimethyl sulfoxide (DMSO), acetyl coenzyme A, diazepam- d 5, and ammonium formate (analytical grade) were from Merck KGaA (Darmstadt, Germany).



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Image Search Results


Journal: RSC Advances

Article Title: A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats

doi: 10.1039/c9ra05785d

Figure Lengend Snippet: Tandem mass-spectrometer working parameters

Article Snippet: Internal standards (ISs) oxycodone-d 6 and diazepam-d 5 were obtained from Cerilliant (Round Rock, TX, USA).

Techniques:

Product ion mass spectra of [M + H] + of oxycodone m / z 316 → 298 (A), oxycodone-d 6 m / z 322 → 304 (B) diazepam m / z 285 → 154 (C) and diazepam-d 5 m / z 290 → 198 (D).

Journal: RSC Advances

Article Title: A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats

doi: 10.1039/c9ra05785d

Figure Lengend Snippet: Product ion mass spectra of [M + H] + of oxycodone m / z 316 → 298 (A), oxycodone-d 6 m / z 322 → 304 (B) diazepam m / z 285 → 154 (C) and diazepam-d 5 m / z 290 → 198 (D).

Article Snippet: Internal standards (ISs) oxycodone-d 6 and diazepam-d 5 were obtained from Cerilliant (Round Rock, TX, USA).

Techniques:

Typical MRM chromatograms of diazepam (left panel) and diazepam-d 5 (right panel) in blank plasma (A), blank plasma with IS1 (B), an LLOQ sample (C), a 3.0 h in vivo sample (D).

Journal: RSC Advances

Article Title: A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats

doi: 10.1039/c9ra05785d

Figure Lengend Snippet: Typical MRM chromatograms of diazepam (left panel) and diazepam-d 5 (right panel) in blank plasma (A), blank plasma with IS1 (B), an LLOQ sample (C), a 3.0 h in vivo sample (D).

Article Snippet: Internal standards (ISs) oxycodone-d 6 and diazepam-d 5 were obtained from Cerilliant (Round Rock, TX, USA).

Techniques: In Vivo